As men progress through the stages of their lives, their health evolves—and so does that of their hair. Hair health can be influenced by a complex interplay of 6 key root causes: hormones, stress, nutrition, metabolism, aging, and lifestyle. Menopause in women is well-known, but fewer people know that men also go through a phase of hormonal shifts at middle life, sometimes referred to as “andropause,” during which they experience a gradual decrease of testosterone.1 In this piece, we’ll discuss how men’s hair changes throughout their lives and how Nutrafol’s physician-formulated Hair Growth Nutraceuticals can help support healthy hair through each stage.
Navigating Hair Health at Different Life Stages: Nutrafol Men vs Nutrafol Men 50+
Product Education
4 Min Read

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Early to middle adulthood: Hormones and stress.
During puberty and young adulthood, men can already start to experience the effects of hormones on their hair.2 In some men, the increase in testosterone leads to an increase in another hormone, called DHT, which can be a key root cause of hair thinning in younger men.2 If a younger man has high DHT levels or a genetic predisposition to be more sensitive to DHT, he may be more likely to experience hair thinning.3
Another key factor impacting the hair in these years is physical or mental stress, often related to education and career goals or starting a family.2
Nutrafol Men is a Hair Growth Nutraceutical that addresses key root causes of hair thinning, like hormones and stress, in men 18 and older—for visibly thicker, fuller hair growth and scalp coverage, without compromising sexual performance.4 It is formulated with 21 ingredients, including a Synergen Complex® with:
Saw Palmetto: Provides concentrated fatty acids clinically shown to reduce the conversion of testosterone to DHT to improve hair growth.
Ashwagandha: A botanical shown to lower cortisol levels for stress-relieving benefits to reduce hair shedding.
Tocotrienol Complex: A concentrated form of vitamin E, a super antioxidant that fights against environmental stress to improve hair density.
Marine Collagen Peptides: A rich source of protein and amino acids that make keratin and builds stronger hair fibers
Hyaluronic Acid: Promotes healthy hair and hydration.
Midlife and beyond: Aging and stress.
As men enter their middle-aged years (50+) and beyond, factors that influence hair health start to shift. Although hormones and life stressors may still be part of the picture, changes related to natural aging, such as collagen breakdown and oxidative stress (at the cellular level), typically start to play a larger role. The key is not to fight the aging process, but to adjust the support we provide to our body and hair as we enter a new life stage.
As we age, we experience a reduction in cellular turnover, clean up, and production).5,6 This can lead to slower hair growth cycles and reduced collagen production, which can weaken the scalp’s structural barrier.7,8 This may also impact nutrition status, as changes in gastrointestinal function, digestion, and functionality of the intestinal wall also tend to slow as we get older.9
Another component is oxidative stress, the imbalance between unstable molecules (free radicals) and protective antioxidants in the body.10 Free radicals may come from lifestyle or environment, like smoking, pollution, or poor diets, and can accumulate with age as our bodies tend to become less efficient at keeping a healthy balance.7,11
Nutrafol Men 50+ is a Hair Growth Nutraceutical that helps maintain and improve hair growth by addressing key root causes of hair thinning, like aging and lifestyle (oxidative stress), for visibly thicker, fuller hair and scalp coverage—without compromising sexual performance.12 It contains the following vegan, biotin-free ingredients:
Moldavian Dragonshead: Clinically tested to promote natural collagen production in the body.
Bacillus subtilis DE111® Probiotic: Optimizes the microbiome to support the breakdown and absorption of nutrients.
Marigold Flower Extract: Reduces oxidative stress.
Curcumin: Extracted from turmeric for its antioxidant properties that fight free radicals to support cellular health.
Tocotrienol Complex: A concentrated form of vitamin E, a super antioxidant that fights against environmental stress to improve hair density.
Hair Support Should Change as You Do.
It’s important to recognize that at different ages and life stages, our bodies and our hair need different support. Nutrafol Hair Growth Nutraceuticals provide physician-formulated support—no matter where men are in life. Our extensive research has helped us to develop a whole-body approach to addressing key root causes of hair thinning as they change throughout different stages of life.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Citations:
Demers LM. Andropause: an androgen deficiency state in the ageing male. Expert Opin Pharmacother. 2003 Feb;4(2):183-90. doi: 10.1517/14656566.4.2.183. PMID: 12562308.
Grymowicz M, et al. Hormonal effects on hair follicles. Int J Mol Sci. 2020 Jul 28;21(15):5342. doi: 10.3390/ijms21155342. PMID: 32731328; PMCID: PMC7432488.
Asfour L, et al. Male Androgenetic Alopecia. 2023 Jan 25. In: Feingold KR, Adler RA, Ahmed SF, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–. PMID: 25905192.
Stephens, T., et al. A prospective six-month single-bling study evaluating changes in hair growth and quality using a nutraceutical supplement in men and women of diverse ethnicities. J Clin Aesthet Dermatol. 2022 Jan;15(1):21-26. PMID: 35309272; PMCID: PMC8903234.
Aman Y, et al. Autophagy in healthy aging and disease. Nat Aging. 2021 Aug;1(8):634-650. doi: 10.1038/s43587-021-00098-4. PMID: 34901876; PMCID: PMC8659158.
Jang H, et al. Aging of hair follicle stem cells and their niches. BMB Rep. 2023 Jan;56(1):2-9. doi: 10.5483/BMBRep.2022-0183. PMID: 36379515; PMCID: PMC9887102.
Reilly DM, et al. A clinical trial shows improvement in skin collagen, hydration, elasticity, wrinkles, scalp, and hair condition following 12-week oral intake of a supplement containing hydrolysed collagen. Dermatol Res Pract. 2024 Jul 10;2024:8752787. doi: 10.1155/2024/8752787. PMID: 39021368; PMCID: PMC11254459.
Pu SY, et al. Effects of oral collagen for skin anti-aging: A systematic review and meta-analysis. Nutrients. 2023 Apr 26;15(9):2080. doi: 10.3390/nu15092080. PMID: 37432180; PMCID: PMC10180699.
Rémond D, et al. Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition. Oncotarget. 2015 Jun 10;6(16):13858-98. doi: 10.18632/oncotarget.4030. PMID: 26091351; PMCID: PMC4546438.
Du F, et al. Oxidative stress in hair follicle development and hair growth: Signalling pathways, intervening mechanisms and potential of natural antioxidants. J Cell Mol Med. 2024 Jun;28(12):e18486. doi: 10.1111/jcmm.18486. PMID: 38923380; PMCID: PMC11196958.
Xu X, et al. Mitochondria in oxidative stress, inflammation and aging: from mechanisms to therapeutic advances. Signal Transduct Target Ther. 2025 Jun 11;10(1):190. doi: 10.1038/s41392-025-02253-4. PMID: 40500258; PMCID: PMC12159213.
Based on a clinical study with 34 men aged 40-65.

