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Understanding Hormones In Perimenopause

Perimenopause often starts quietly—a skipped period here, a hot flash there, a wave of anxiety or sleeplessness. It’s easy to brush off or feel confused by these changes. But at the center of it all is something powerful and real: the hormonal shift taking place in your body.

Hormones are your body’s chemical messengers. During your reproductive years, four key hormones—estrogen, progesterone, follicle-stimulating hormone (FSH), and luteinizing hormone (LH)—help maintain the relatively predictable rhythm of the menstrual cycle. But their impact goes far beyond reproduction, influencing nearly every function in your body, from mood to metabolism.

During perimenopause, hormones shift in unfamiliar and often overwhelming ways. Understanding these hormonal changes is the first step to feeling in control and connected to your body again.

  • Body temperature: Progesterone increases basal body temperature after ovulation, a key indicator of fertility.

  • Sleep quality: Estrogen supports deep, restful sleep. When levels drop, sleep can suffer.

  • Mood and cognition: Estrogen and progesterone influence key neurotransmitters, such as serotonin and dopamine.

  • Metabolism: Estrogen and progesterone help regulate energy use. As they decline, metabolism slows and weight gain becomes more common.

  • Heart rate variability: Fluctuations can occur during the luteal phase, when progesterone levels peak.

  • Hair health: Estrogen decline can shorten the hair growth phase. DHT, a form of testosterone, can cause follicles to shrink, leading to thinning.

  • Skin: When estrogen levels dip, skin can feel drier, thinner and more prone to fine lines and irritation.

Smart Patterns. Real Tracking. Better Answers.

I firmly believe that with the right tools, knowledge, and support, women can face perimenopause with confidence. As a physicist, I’ve always trusted science to help us make sense of our bodies. I first developed the Natural Cycles Birth Control algorithm to support myself and others seeking a non-hormonal contraceptive option, grounded in temperature-based fertility science. 

Now in my 40s, I’m focused on creating better tools to help women understand where they are in the hormonal transition—and what comes next. That’s why we built NC° Perimenopause. Unlike traditional symptom trackers, our smart tool combines temperature data, symptoms, and our proprietary algorithm to identify meaningful patterns and deliver personalized, clinically informed insights. Whether it’s making small lifestyle changes, exploring targeted supplements, or knowing when it might be time to start a conversation about hormone replacement therapy, NC° Perimenopause is designed to help you move forward with clarity and support.

The Menopause Edit readers can get exclusive access to NC° Perimenopause here.

Dr. Elina Berglund is a physicist and the creator of Natural Cycles, the first FDA-cleared birth control app. After helping to discover the Higgs boson, she shifted her scientific focus to reproductive health, developing tools to empower women with personalized, data-driven insights—from ovulation to perimenopause and beyond. She shared her expertise as a part of Nutrafol's partnership with Natural Cycles.

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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.